Anogenital distance and variability in semen parameters

Shorter Anogenital Distance Predicts Poorer Semen Quality in Young Men in Rochester, New York

BACKGROUND In male rodents, anogenital distance (AGD) provides a sensitive and continuous correlate of androgen exposure in the intrauterine environment and predicts later reproductive success. Some endocrine-disrupting chemicals can alter male reproductive tract development, including shortening AGD, in both rodents and humans. Whether AGD is related to semen quality in human is unknown. OBJ...

Anogenital Distance in Turkish Newborns

We have measured anogenital distance (AGD) in 300 newborns delivered in Zubeyde Hanim Maternity Hospital in 2007. As in the study by Ozkan et al (1), we also used a sliding caliper for the measurements; however, in the manuscript by Ozkan et al (1), it was mentioned as tape, which needs correction. The results of both Dr Ozkan’s study and ours seem similar. We could not give the results of meas...

Anogenital Distance in Turkish Newborns

OBJECTIVE Anogenital distances are considered to be a sensitive indicator of external genitalia exposure to factors such as anti-androgens, and/or endocrine distruptors during the prenatal period. Exposure to such factors can lead to changes in the anogenital measurements (AGM) of newborn infants. These measurements can be used to predict masculinization of the external genitalia in healthy new...

Semen Parameters and Chromatin Packaging in Microsurgical Varicocelectomy Patients

Prenatal Phthalate Exposures and Anogenital Distance in Swedish Boys

BACKGROUND Phthalates are used as plasticizers in soft polyvinyl chloride (PVC) and in a large number of consumer products. Because of reported health risks, diisononyl phthalate (DiNP) has been introduced as a replacement for di(2-ethylhexyl) phthalate (DEHP) in soft PVC. This raises concerns because animal data suggest that DiNP may have antiandrogenic properties similar to those of DEHP. The...